Health risks of consuming spoiled wine Typically, wine spoilage occurs due to oxidation, meaning that the wine may turn to vinegar. Although it may taste unpleasant, it is unlikely to cause harm. However, spoilage due to microbes may result in food poisoning.
Drinking old wine will not make you sick. Drinking wine that has gone off will most certainly be an unpleasant experience but you are unlikely to get sick. Only about 1% of wines improve with aging as the majority are made to consume within months of bottling.