All Guinness Draught is brewed in Dublin,Ireland at the Guinness brewery. The Guinness Draught in the US and everywhere else is exactly the same as it is in Ireland. The other Guinness products are brewed at various breweries around the world. Guinness owns 5 breweries, three of which are in Africa.
It differs slightly from the version sold in Ireland, the UK, and the U.S. in that it's carbonated, not nitrogenated, and has a higher alcohol volume—a holdover from the brewing techniques Guinness first used when making stout in Africa.