There are some major differences between tequila and vodka, though they are both distilled spirits: Tequila is made from the blue agave plant and vodka is made from a starch or sugar rich plant. Tequila is distilled into five different types, while vodka only has one form. Tequila has varied taste and vodka doesn't.
Calorie differences vodka, tequila fares better and has fewer calories per shot than vodka. Vodka, is a type of alcohol, tend to be higher in calories.